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Mutations in UPSrelated genes, such as parkin and UCHL1 , compromise ubiquitin tagging or removal, hindering substrate recognition and clearance [169]

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Since in some cases gshA and gshB fuse to form a single gene gshF and sequence divergence is very high for both GshA and GshB [3], the results of GshA, GshB and GshF were manually checked for the position of alignment in the gene and length of the hit

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