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Mouse islets express lower levels of reactive oxygen species (ROS) clearing enzymes, such as glutathione peroxidase (GPX), superoxide dismutase (SOD) and catalase than several other tissues

For example, pH-responsive nanocarriers utilize the acidic environment of tumors to alter the conformation of the carrier, further inducing drug release and ensuring local activation (Panja et al., 2025)

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Wu M, Lu G, Lao YZ, Zhang H, Zheng D, Zheng ZQ, Yi J, Xiang Q et al (2021) Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice

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