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Description

Many cancers rely on oxidative phosphorylation (OXPHOS) and aerobic mitochondrial metabolism [10], based on a tricarboxylic acid (TCA) cycle and fatty acid -oxidation (FAO)

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Hexosamine biosynthesis pathway The hexosamine biosynthesis pathway (HBP) is an important glucose metabolism pathway that synthesizes uridine diphosphate-N-acetyl glucosamine (UDP-GlcNAc), which is subsequently utilized for post-translational modification (O-GlcNAcylation) of intracellular proteins that regulate nutrient sensing and stress responses

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