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Compared with normal animals, Nrf2-deficient mice have more pronounced effects on lipopolysaccharide (LPS)-induced microglial activation and inflammatory response, with lower levels of IL-1, IL-6, IL-12, and TNF- in the brain ( Moreover, increasing evidence indicated that Nrf2 may regulate mitochondrial function and metabolism

National Health and Nutrition Examination Survey data found that the normal serum MMA range for the 2.5th to 97.5th percentile of people 70 years, who were considered to be vitamin B12-replete and with normal kidney function, was 84 to 317 nmol/l (Mineva, 2019)

Advances in the Treatment of Acute Myeloid Leukemia: New Drugs and New Challenges

Frontiers of Environmental Science & Engineering, 10(1), 168176

Even when a compound has a legitimate biological function, poor manufacturing practices can reduce its effectiveness