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doi: 10.3390/nu11092022 27 ForouhiNGKoulmanASharpSJImamuraFKrgerJSchulzeMBet al

PMID: 37 WangYFuXLiH

It is one of the most studied peptides in cellular signalling research, referenced extensively for its interactions with collagen synthesis pathways, antioxidant gene expression, and tissue remodelling mechanisms

Other experiments demonstrated that nitrate and nitrite exposure produced no cytotoxicity in glutathione-depleted HA1 cells and that coincubation of NO-saturated medium with oxyhemoglobin inhibited NO-induced cytotoxicity in glutathione-depleted HA1 cells