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Therapeutic efficacy of bromelain in impacted third molar surgery: A randomized controlled clinical study

Circulation 113(1):7480 Moreno-Estrada A, Gignoux CR, Fernandez-Lopez JC, Zakharia F, Sikora M, Contreras AV, Acuna-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuno-Arana I, Barquera-Lozano R, Macin-Perez G, Granados-Arriola J, Huntsman S, Galanter JM, Via M, Ford JG, Chapela R, Rodriguez-Cintron W, Rodriguez-Santana JR, Romieu I, Sienra-Monge JJ, del Rio Navarro B, London SJ, Ruiz-Linares A, Garcia-Herrera R, Estrada K, Hidalgo-Miranda A, Jimenez-Sanchez G, Carnevale A, Soberon X, Canizales-Quinteros S, Rangel-Villalobos H, Silva-Zolezzi I, Burchard EG, Bustamante CD (2014) Human genetics

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Tumor cells exhibit altered iron regulation, which is intricately linked to the pathophysiology of cancer, including tumor metastasis, development, and particularly, drug resistance

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Endogenous and exogenous antioxidants, which inhibit oxidative stress, function to counter these effects in the body