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While most extensively studied in AD models, their shared mechanism supports their potential relevance in PD and other age-related neurodegenerative conditions, including counteracting glutathione depletion, lipid peroxidation, and metabolic dysfunction

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Cell 108 , 837847 (2002)

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Multiple factors, such as organelles (mitochondria, lysosomes) and microenvironmental conditions (e.g., ROS), regulate diverse forms of cell death, highlighting its complexity through interwoven signaling pathways and their crosstalk [24]

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