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This condition, mainly caused by bacterial infections, oxidative stress, high-fat diet, exposure to alcohol or chronic allergens, and dysbiosis, appear to be highly connected with the development and/or progression of several metabolic and autoimmune systemic diseases, including obesity, non-alcoholic fatty liver disease (NAFLD), neurodegeneration, cardiovascular disease, inflammatory bowel disease, and type 1 diabetes mellitus (T1D)

Rich in phenolic and flavonoid metabolites, Scrophularia radix inhibits -glucosidase and -amylase, activates the AMPK pathway, and regulates glucose metabolism while alleviating insulin resistance

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In addition, other foods can either release histamine in the body or inhibit DAO production

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