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The complex interplay between antioxidants and ROS in cancer

Higher uptake of BV2-metformin-loaded PLGA was observed in BV2 cells compared to SH-SY5Y, indicating preferential targeting to microglia

The mechanism may be related to curculigoside significantly reducing AD-promoting factors (e.g., A1-42, p-tau) and increasing ferroptosis protective factors (e.g., GPX4, SLC7A11, GSH) in the hippocampus and cortex of AD mice, 574 suggesting that the natural compound curculigoside can be used as a promising therapeutic agent to improve AD by inhibiting ferroptosis

Alexandria J Med 54:287293

Y., and Xie, X

Pack AM, Oskoui M, Roberson SW et al (2024) Teratogenesis, perinatal, and neurodevelopmental outcomes after in utero exposure to antiseizure medication: Practice guideline from the AAN, AES, and SMFM