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Description

Analgesic mechanism of Sinomenine against chronic pain

The N-terminal -helix governs membrane-mediated aggregation by anchoring the protein into the membrane (Pandey et al., 2018)

10.1038/nn.4030 130 EscartinC.GaleaE.LakatosA.O'CallaghanJ

Bioinformatics processing and statistical analysis of the metabolomic data The metabolomics analyses obtained from cells and media extractions were log2 transformed and the replicates normalized using quantile normalization