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In an experimental model of methamphetamine-induced neurotoxicity, Nourolapour, Abbassi Daloii [239] demonstrated that aerobic exercise and crocin supplementation significantly upregulated hippocampal neuroprotective gene expression, including BDNF and TrkB, which are critical for neuronal survival and plasticity

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Inhibition of GAPDH caused energy stress in the highly glycolytic mutant cell lines, leading to cell death

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Rosenkranz A, Slastnikova T, Durymanov M, Sobolev A

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