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Site-directed mutagenesis was performed using QuikChange II XL following the manufacturers instructions

In obesity, NO bioavailability is often reduced, contributing to insulin resistance and increased adiposity

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In ischemia-reperfusion injury, CAMs mediate the adhesion of immune cells to the endothelium of blood vessels, facilitating their migration to the site of injury

These investigations outlined a distinct mechanism to cope with ferroptosis and implied that FSP1 may serve as a therapeutic target for personalized cancer therapy