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doi: 10.1038/ng2108

Energy and Vitality Mitochondria are the "powerhouses" of your cells

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In addition, the mitogen-activated protein kinase (MAPK) insulin pathway is the basis of many obesity-related malignancies that control cell growth and mitosis (36), whereas insulin can directly promote cell proliferation and survival via the phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) and Ras/MAPK pathways (37)

Those who had the greatest percent change in that ratio also had a greater percent change in their levels of glutathione in their brains