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FGF21 analogs therefore represent a promising emerging class of NASH therapeutics, as a number of them have demonstrated pleiotropic effects consistent with improved liver health and whole-body metabolism

PMC 2147980

6 Limitation and Future perspective Although current research has revealed the critical role of ferroptosis in the pathological progression of AD, several limitations remain to be addressed in this field: (1) Existing evidence primarily relies on animal models or in vitro cellular experiments, failing to comprehensively reflect the spatiotemporal dynamics of iron metabolism dysregulation in the brains of human AD patients

H.Martinez-ClimentJ

In 2021, Zhang et al

Selenoproteins: molecular pathways and physiological roles