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The anti-inflammatory effects of AC have been strongly related to its antioxidant role, where in an osteoarthritis rat model, the reduction in NF-B was accompanied by diminished reactive oxygen species (ROS) production (Ma et al

PubMed Central, Overgaard, Ulrik M., et al

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20 Astroglial reactivity can now be defined as an evolutionarily conserved, graded, and multi-stage primarily defensive reaction of astrocytes to neuropathology