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YAP and WWTR1: new targets for skin cancer treatment

Mutations in the MTHFR gene can result in lower levels of or less functional MTHFR enzyme

However, those with severe allergies should consult their healthcare provider before starting treatment to ensure it is suitable for their specific health condition

Tepotinib is another nonselective c-MET inhibitor that is being investigated in a Phase II study (NCT04647838) in patients with solid cancers harboring c-MET amplification or exon 14 mutation who progressed after standard treatment for metastatic disease, including mCRC

Vidrio E, Jung H, Anastasio C

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