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Finding the variables that are linked to a prominent risk of getting CKD is crucial, including hypertension, diabetes mellitus, metabolic syndrome, glomerulonephritis, genetic diseases, urological disorders (obstruction, recurrent urinary infections), infections, vasoconstriction, (NSAIDs, antibiotics, light chains), dyslipidaemia, tubular cell toxicity, interstitial nephritis, crystal deposition, and proteinuria as nephrotoxins that affect intra-glomerular hemodynamics

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doi: 10.15272/ajbps.v4i40.645 13

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Outside of those conditions, the safety profile is much less clear