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The basic idea involves a linkage of a nuclear hormone to a peptide, usually through a linker that would allow metabolism of the nuclear hormone only within the targeted cell reducing the undesirable effects in other tissues

(PubMed) Disclaimer The Linus Pauling Institute's Micronutrient Information Center provides scientific information on the health aspects of dietary factors and supplements, food, and beverages for the general public

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If we answer the question of who such approaches are considered for, first and foremost these are patients for whom it is important to slow progression rather than simply eliminate symptoms

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