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The introduction of GOx is another strategy for the development of glucose-responsive materials, as GOx catalyzes the conversion of glucose into gluconic acid, which generates electrostatic repulsions through protonation and causes the matrix to swell, thereby facilitating drug release [327, 328]

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Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension

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Semaglutide, the active ingredient in Wegovy, works through multiple mechanisms to support weight management efforts

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