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In support of this idea, when holoTC concentrations were subtracted from total vitamin B-12 concentrations, the remaining vitamin B-12, represented by the holohaptocorrin (holoHC) fraction of serum vitamin B-12, was unaffected by the concentration of plasma folate (Figure 8B)

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This review examines the core molecular mechanisms of ferroptosis and cuproptosis and delineates their respective roles in OSCC initiation, progression, immune evasion, and therapeutic resistance

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