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It is commonly referenced in preclinical and laboratory research examining neuropeptide signalling, circadian rhythm regulation, and central nervous systemrelated biochemical pathways within controlled research systems

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Moreover, patients in the HGSH group showed a higher incidence of postoperative recurrence and metastasis ( P = 0.003) (Table 3), as well as reduced DFS ( P = 0.001) and OS ( P = 0.026) (Fig