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24 Patient experiences Data from a review of patient experiences and surveys involving more than 2200 patients with B 12 deficiency in the UK indicate that many patients have concerns related to healthcare quality, safety, and treatment, 62 63 64 with nearly two thirds of respondents reporting that their treatment is insufficient to manage symptoms

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Chronic tendinopathy that has persisted for months or years often requires longer treatment of 6 to 8 weeks or more

The absence of clinically validated ingredients, either natural or pharmaceutical, is a major limitation

Competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper