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To expand our knowledge of the underlying molecular mechanism of OsDHAR activity against ROS, high-resolution crystal structures of the apo-form, AsA-bound and GSH-bound OsDHAR were examined at 1.9, 1.7 and 1.7 resolution, respectively

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Interestingly, exogenous HGF did not promote spherogenicity under these culture conditions, however, profound induction of sphere formation was seen when EGF and FGF were omitted from the medium in ZH-161 and ZH-305 except T-269