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Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease

The activated NLRP3 inflammasome will cause rapid activation of pro-inflammatory factors in the intestinal tract, and continuously cause cellular autophagy, which step by step exacerbates the inflammatory response, leading to more and more severe intestinal injury

Table 2 : Adverse Reactions (10%) in Patients Who Received XELODA for Adjuvant Treatment of Colon Cancer in X-ACT Clinically relevant adverse reactions in 30%) were anemia, diarrhea, palmar-plantar erythrodysesthesia syndrome, hyperbilirubinemia, nausea, fatigue, and abdominal pain

& Suk, K.Metabolic reprogramming by the pyruvate dehydrogenase kinaselactic acid axis: linking metabolism and diverse neuropathophysiologies

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I've had all of those effects