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Since this model results in extremely elevated and debilitating glucose levels, titration to non-toxic levels of hyperglycemia was achieved with daily injections of long-acting insulin glargine ( Fig

Additionally, probiotics stimulate the production of mucins, the glycoproteins that form a protective mucus layer over the intestinal epithelium (107), further strengthening the gut barrier and providing an additional line of defense against pathogens and toxins

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Male WT mice and male GLP-1R knockout mice, aged 713 weeks with weighing 2030 g were included in this study [29]

Acknowledgements While preparing the manuscript, the authors used ChatGPT to frame complex information into a cohesive outline while maintaining intellectual integrity