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6.2 Interventions for renal metabolic barrier injury Renal metabolic barrier injury involves multiple pathological disorders including glomerular filtration, renal tubular transport and renal interstitial homeostasis

The fatty acid metabolism process involving mitochondria includes fatty acid synthesis (FAS) and FAO

Culturing primary B-ALL cells or Reh lymphoid cell line with bone marrow-derived MSCs under hypoxic conditions induces a higher expression of HIF-1 and therefore an acquisition of the glycolytic phenotype of leukemic cells, which in part is due to signaling-regulated by the AKT/mTOR pathway induced by stromal cells

Cell Biol Int 45:21612177

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