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Laboratory tests have revealed that extracellular GMFB can decrease the number of RPECs and their cellcell connections and increase ACSL4 expression (35)

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PMID: 40815947 Phytomedicine Rg3 inhibits hypoxia-induced tumor exosomes from boosting pancreatic cancer vasculogenic mimicry through the HIF-1/LARS1/mTOR axis

290,291 Another proposed mechanism is that mTOR regulates the crosstalk between mitochondria and the nucleus, stabilizing the key protein Clk-1, which is essential for mitochondrial signaling communication