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Iron is deposited in the brain cells of AD patients, and excessive iron will exacerbate oxidative damage and cognitive deficits (Bao et al., 2021)

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This is essentially an acknowledgment of prolotherapys potential: SI joint pain in EDS is notoriously hard to treat (regular surgery is rarely a good option), so a successful prolotherapy outcome represents a valuable solution

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Numeric data are expressed as the mean standard deviation (SD) and were analyzed by one-way ANOVA followed by LSD test

Behavioral measures: The following standardized behavioral measures were completed by primary caregivers for both the ASD and TDC groups: the Adaptive Behavior Assessment System-II (ABAS-II)( Harrison: Adaptive Behavior Assessment System - Google Scholar , n.d.) or the updated version, the ABAS-3 (N=34), and The Social Responsiveness Scale (SRS-2)( Constantino: Social Responsiveness Scale: SRS-2 - Google Scholar , n.d.) groups