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Doxorubicin (50, 37.5, 25, 12.5 and 10 M) was injected into the media 16 minutes into the experiment (between measurements 1 and 2), yielding concentration-dependent oxygen consumption profiles in a cell-free environment

Introductory chapter: macrophages more than sentinel innate immune cells

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Furthermore, GPX4 deficiency significantly decreased the number (Figure 1F), proliferation (Figure 1G), and IFN- production (Figure 1H) of CD8 + T cells, and diminished completely the capability of exogenous GSH to promote the expansion and function of CD8 + T cells

This review highlights the need to further investigate the precise mechanisms of Cu interactions with infections, immune inflammation, etc., in the context of respiratory diseases, and to explore the potential of therapeutic strategies for Cu, cuproptosis, and other related effects