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There is normally a feedback mechanism that regulates glycocalyx synthesis and degradation, but the rate of degradation is much higher than the rate of synthesis in the pathologic state

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Further, the treatment prevented degeneration of myelinated fibers and accentuated the axon circularity [51]

IOM 2011)

Jha JC, Gray SP, Barit D et al (2014) Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy

The latter is encoded by UGA and directed by the selenocysteine insertion sequence, SECIS element [28, 29], which serves as a platform for the recruitment of elongation factors of selenocysteine-tRNA [Ser]Sec (Sec-tRNA [Ser] Sec ) translation that decodes the UGA codon for the whole family of selenoproteins