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The photosensitizer molecules in the high-energy excited state transfer energy directly to the surrounding 3 O 2 , generating cytotoxic 1 O 2 and promoting apoptosis of tumor cells [188]

Deep sequencing indicated that miR-21-5p and/or miR-NC are involved in this phenomenon ( Figure 4C )

Toxicol Appl Pharmacol 207(2):179186 International Transporter, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL et al (2010) Membrane transporters in drug development

An antioxidant deficiency can damage liver cells

More importantly, we discovered that GPX1 can partially block the nuclear translocation of NF-B p65 and inhibit the activation of the NF-B signaling to protect SGNs against peroxynitrite damage

An overview of recent studies on microbiome-targeted therapies, their main outcomes, and limitations is presented in Table 4