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125 Experimental models suggest that coffee constituents promote neuronal development and increase antioxidant defense systems in the brain

However, this does not explain the fact that, in the ER, the ratio of reduced to oxidized glutathione ([GSH]:[GSSG]) is optimal for disulphidebond formation (Lyles & Gilbert, 1991)

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13.11.6 Colorectal cancer Colorectal cancer ranks as the fourth most diagnosed malignancy in high-income countries and the fifth in low-income regions