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Under normal physiological circumstances, glutamate resides in presynaptic vesicles and is released into the synaptic cleft at high concentrations following neuronal depolarization 62

C.Reddy KethireddyS.ContractorR.et al

That cysteine, sulfite and other sources of sulfates can serve as precursors for GAG synthesis has been well established [5658]

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From the training set (n=4,726), we applied five machine learning algorithms based on 100 datasets derived from repeated 5-fold cross-validation, including adaptive boosting, extreme gradient boosting, light gradient boosting machine, logistic regression, and random forest classifier

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