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Depletion of mitochondrial GSH is associated with cellular senescence, compromised energy production, and age-related pathology (910)

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Introduction Glutamate is one of the main excitatory neurotransmitters of the CNS, contributing to normal neural transmission, development, differentiation, and plasticity

Resveratrol, a known activator of SIRT1, reduced TSA-mediated acetylation and ubiquitination of SOX2, thereby enhancing the colony-forming ability as well as osteogenic and adipogenic differentiation of BM-MSCs in a dose-dependent manner

Pathological effects generally arise only when the mutant load exceeds a threshold [162]