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Lemes, S

Modulation of redox homeostasis: a strategy to overcome cancer drug resistance

[21] Clomipramine has been reported as being less toxic in overdose than most other TCAs in one meta-analysis but this may well be due to the circumstances surrounding most overdoses as clomipramine is more frequently used to treat conditions for which the rate of suicide is not particularly high such as OCD

Once formed, these reactive radicals can initiate chain reactions resulting in a cascading negative effect on many other molecules within cells and cell walls, which in turn causes oxidative stress within the animal

They are widely present in the plant kingdom, serving as an important class of natural substances in plants, and exhibit functions such as antioxidant, anti-inflammatory, antibacterial, antiviral, and antitumor activities

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