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Wijnholds, J

Campion SN, Johnson R, Aleksunes LM, Goedken MJ, van Rooijen N, Scheffer GL, Cherrington NJ, Manautou JE

2.3 Genetic susceptibility: shared genetic architecture EDC exhibits significant genetic susceptibility, with its comorbidity risk potentially influenced by shared genetic variants

Natural History/Prognosis CVS resolves, in most children (5070%) in late childhood or early adolescence (2830, 73, 74)

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In summary, although evidence for single intervention strategies varies, given the complexity of CP/CPPS pathology, the most feasible future direction lies in constructing multi-target combination intervention regimens covering anti-inflammation + antioxidation + endocrine correction + microecological regulation based on patient phenotypic stratification, with the aim of achieving the dual goals of symptom relief and fertility protection ( Table 1 )