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Large-scale randomized clinical trials are required to define optimal dosing strategies, treatment windows, and long-term safety profiles, particularly in populations without overt reproductive pathology (Gong et al., 2025)

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10.1093/bjd/ljae507

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6 Conclusions The expanding corpus of empirical evidence underscores luteolin as a potentially effective neuroprotective nutraceutical, exhibiting multimodal mechanisms that specifically address the fundamental pathological processes associated with NDDs