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Topical application of GHK-Cu dressings 2 daily for 8 weeks vs standard wound care

S., Wang, J

Much simpler than topical applications

7 In rats treated with cysteamine (which depletes somatostatin and dysregulates GH release), BPC-157 administration normalized GH receptor expression in peripheral tissue and attenuated the duodenal lesions characteristic of cysteamine-induced damage

Commonly used for skin brightening, glutathione helps reduce melanin production and promotes a more even-looking complexion over time

These differences may reflect tissue-specific interactions or compensation by other DUBs, highlighting the need for further study of USP9X and other DUBs roles in circadian regulation across tissues