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In some studies, based on the intraperitoneal infusion of LPS in mice models, it was observed an increase in pro-inflammatory cytokines, such as IL8 and TNF alfa, but also the appearance of autoantibodies against ox LDL, the accumulation of inflammatory infiltrate in the vascular intima, and an increasing aortic atherosclerosis [64]

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With age, levels naturally decline

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Of those, 8% (44)[2] were issued for medical devices