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Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Schmid-Burgk, J

A similar approach was then used for the data acquired herein with POPE 13 C-MRS in mice

The well-resolved FTIR peaks further support the successful functionalization of both SNCDs and SBA-15 MSN, confirming the presence of critical chemical groups necessary for drug conjugation and responsive behavior

R Substrates conjugated with amino acids include: Benzoic acid (from toluene exposure, food preservatives, and gut bacterial metabolism of polyphenols), conjugated with glycine to form hippuric acid R Bile acids (conjugated with glycine or taurine for proper emulsification and excretion) R NSAIDs and other acyl group drugs Phenylacetic acid (from phenylalanine metabolism), conjugated with glutamine to form phenylacetylglutamine R Salicylic acid (aspirin metabolite), conjugated with glycine to form salicyluric acid R Glycine conjugation is the most common amino acid conjugation

Portincasa 2012)