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Choose a site either for a subcutaneous injection directly over the area or an intramuscular injection into the adjacent deltoid muscle

Consistent with other reports regarding C-terminal truncations of its ortholog HNF4 61 , truncating the ligand-binding domain of NHR-49 altered its nucleocytoplasmic distribution, favoring a more pronounced nuclear localization under ad libitum feed conditions when compared to the full-length receptor (Fig