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In a randomised, double-blinded, placebo-controlled trial, oral N-acetylcysteine (NAC), a thiol-containing agent which promotes glutathione synthesis [75] and scavenges hydrogen peroxide, hydroxyl radical and hypochlorous acid, was added to the standard therapy (prednisone plus azathioprine) of IPF patients [76]

This could indicate the possibility of gene duplication events in the formation of close APX homologs

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