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Oral Melanotic Macule: Symptoms and Treatment Skinsight Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown melanotic macule gingiva have had for years COM August 2004 Diagnosis Congenital Melanotic Macule of the What Caused These Multiple Hyperpigmented Macules of the Mouth? Pigmented lesions of the oral cavity: An Update PMC Oral Melanotic Macule: a small dark spot in the mouth ArtSmiles
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