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Supplementing with riboflavin altered the DNA methylation in people with MTHFR C677T, causing a decrease in methylation of the ACE gene.[ref] Benefits of supplemental riboflavin: Clinical trial data Clinical trials are an excellent way to know if a supplement is effective for most people

Eur Respir J 46:10331045 Griffin JE, Gawronski JD, DeJesus MA, Ioerger TR, Akerley BJ, Sassetti CM (2011) High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism

B12 injections can ensure that older adults maintain adequate levels of this essential nutrient, supporting their energy levels and cognitive functions

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