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Many gut bacteria need low-oxygen environments to survive

Acknowledgements We thank Alainaa Refaie and Dessalegn Lamesgen Chnie, who have polished the manuscript

452 Clinically, oral budesonide (9 mg daily) is safe and effective for clinical and endoscopic remission in patients with mild to moderate UC that is refractory to mesalazine

Your medical provider will help determine the best schedule for you

doi: 10.3389/fnagi.2026.1729015 Received 20 October 2025 Revised 30 January 2026 Accepted 09 February 2026 Published 27 February 2026 Volume 18 - 2026 Edited by Ashok Kumar, University of Florida, United States Reviewed by Jessica N