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J Mol Struct 1316:139037

This accumulation, in turn, fuels a vicious cycle of chronic low-grade inflammation, which further exacerbates immunosenescence and accelerates the aging process

Therefore, inhibition of hyperactivated mTOR may represent promising therapeutic targets for AD (Cassano and Magini 2019).Similarly, in the pathogenesis of MS, peripheral immune cells penetrate the BBB into the brain and destroy myelin membranes and neurons (Alavi and Fanoudi 2023)

The mechanism of oxidative cell death Excessive ROS can directly damage organelles, including the plasma membrane, ultimately leading to cell death [71]

Am J Gastroenterol (2013) 108:163443

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