glutathione low elevated ferritin IV Liver Detox Explained Ferroptosis regulation in lysosome Lysosomal

Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Correlation of ferritin and glutathione peroxidase 4 (GPX4) level as a marker of ferroptosis process in endometrioma Scientific Reports Glutathione scavenging natural derived ferroptotic nano amplifiers strengthen tumor therapy through aggravating iron overload and lipid peroxidation ScienceDirect Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11 Mediated Ferroptosis Circulation Research Hyperferritinemia and inflammation PMC Spotlight on iron overload and ferroptosis: Research progress in female infertility ScienceDirect

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