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Dysfunction of the microbiota leads to decreased BA activity, reducing unconjugated BA and secondary BA production, weakening FXR activity, and exacerbating cirrhosis through various pathways: (1) In hepatocytes, FXR interacts with nuclear receptors such as peroxisome proliferator-activated receptors (PPAR)- and liver X receptor (LXR) to form heterodimers, regulating downstream target gene expression

Comparative transcriptional profiling analysis of developing melon (Cucumis melo L.) fruit from climacteric and non-climacteric varieties

First and foremost, no purification occurred under these conditions

10.1016/j.phymed.2024.155814 119 WuD.CederbaumA

Despite the few studies cited above in children, dietary exposure assessments remain limited in Cameroon, emphasizing the need for routine surveillance, food safety education, and policy enforcement to protect children from ongoing mycotoxin risks in Cameroon

This research was supported by the Scientific Research Fund of the Yunnan Provincial Department of Education (Project No