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Transzonal projections: Essential structures mediating intercellular communication in the mammalian ovarian follicle

This requirement becomes particularly critical during high-intensity exercise when muscle demand for blood volume increases proportionally

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In the most apical region of the epithelium there is an intercellular gap (around 90 ) named zonula occludens or tight junctions, followed by the zonula adherens (gap of 200 ), followed by the macula adherens or desmosomes (gap of ~240 ) ( zonula occludens (ZO) family