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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

Possible involvement of oxidative stress in piperonyl butoxide induced hepatocarcinogenesis in rats

It's also studied for gut health, and is commonly used by athletes and in injury-recovery research, though it isn't an approved medication

Reproduction 143:281295 Assis DM, Zalazar L, Juliano MA, Castro RD, Cesari A (2013) Novel inhibitory activity for serine protease inhibitor Kazal type-3 (SPINK3) on human recombinant kallikreins

Assessment and improvement of statistical tools for comparative proteomics analysis of sparse data sets with few experimental replicates

The reconstituted product has a pH of approximately 7.4